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Key Takeaways:
- Mary-Catherine Lader exits Uniswap after four impactful years, remaining as an advisor temporarily.
- Under her guidance, Uniswap secured major funding and overcame SEC scrutiny.
- UNI’s price and trading volume remain strong, signaling confidence in the platform’s future.
Mary-Catherine Lader, the President and Chief Operating Officer of Uniswap Labs, has announced her departure after serving the company for four years. Her exit comes as a significant moment for the decentralized finance (DeFi) ecosystem, especially given her role in shaping Uniswap’s strategic direction during a period of growth and regulatory tension.
While Lader will continue in an advisory capacity during the transition, no successor has been named as of this writing.
Lader’s Legacy: Growth, Regulation, and a Billion-Dollar Valuation
During her leadership, Uniswap Labs achieved notable milestones. Most prominently, in October 2022, the platform secured a $165 million Series B funding round led by Polychain Capital. This placed the company’s valuation at around $1.66 billion, solidifying Uniswap’s status as Ethereum’s leading decentralized exchange.
Personal news: after four incredible years as President & COO of @Uniswap, I’m starting something new.
— Mary-Catherine Lader (@Mclader) July 15, 2025
This is a new chapter for crypto. We’ve come a long way since I started digital assets at BlackRock in 2015, and building with @haydenzadams was an awesome adventure.
I’m…
More recently, Uniswap received a regulatory boost when the U.S. Securities and Exchange Commission (SEC) ended its investigation—originally sparked by a Wells Notice in April 2024—without pursuing any enforcement action. Lader’s leadership during this legal scrutiny earned praise from key figures in the industry.
Community Reacts to Uniswap’s Leadership Shakeup
Lader’s resignation drew a range of responses. Critics like Martin Shkreli used the opportunity to question her political stance, accusing her of undermining crypto’s decentralization ethos. However, many voices in the industry expressed gratitude and support.
Coinbase CEO Brian Armstrong congratulated her on social media, stating, “Appreciate your leadership at Uniswap over the years.” Meanwhile, Lader herself hinted at a new venture, posting on X, “This is a new chapter for crypto…I’m excited to scale from here.”
you guys tried to kill crypto voting for dems, good riddance
— Martin Shkreli (@MartinShkreli) July 15, 2025
UNI Token Remains Resilient Despite Executive Exit
Uniswap’s native token, UNI, has shown strength despite the leadership transition. On July 15, UNI dipped to $8.74 but rebounded to $9.16 within 24 hours—a 2.28% gain, according to CoinMarketCap.
Also Read: Polygon Surpasses $100B on Uniswap, Reinforces Its DeFi Dominance
Technical indicators also pointed toward bullish momentum. The Relative Strength Index (RSI) held firm at 67, suggesting continued upward pressure. Additionally, the MACD showed positive divergence, reinforcing investor confidence.
Uniswap also recorded over $73 billion in 30-day trading volume per DefiLlama, affirming its operational resilience and dominant market position.
Disclaimer: The information in this article is for general purposes only and does not constitute financial advice. The author’s views are personal and may not reflect the views of Chain Affairs. Before making any investment decisions, you should always conduct your own research. Chain Affairs is not responsible for any financial losses.
I’m a crypto enthusiast with a background in finance. I’m fascinated by the potential of crypto to disrupt traditional financial systems. I’m always on the lookout for new and innovative projects in the space. I believe that crypto has the potential to create a more equitable and inclusive financial system.
